Methylcobalamin and cyclocobalmin are both forms of vitamin B12, but they differ in their chemical structure, function, and use in the body. Let's dissect this further and truly understand the differences between these two forms.

Chemical Structure:

Methylcobalamin - This is a naturally occurring form of B12 as it contains a methyl group that is attached to the cobalt ion in its structure. Methylcobalamin is a cofactor for enzymes that are involved in biological reactions and are necessary for maintaining the peripheral nervous system.

Cyclocobalamin - This is a synthetic and less common form of vitamin B12. Its structure includes a cyclic ligand around a cobalt ion.

(Ligand - an ion or molecule attached to a metal atom by coordinate bonding)

Function in the Body:

Methylcobalamin - It is an active form of vitamin B12 that plays a crucial role in the methionine synthase reaction. This is essential for DNA synthesis and regulation, as well as the production of neurotransmitters which allow neurons to communicate with each other throughout the body to provide a variety of bodily functions.

Cyclocobalamin - This form of vitamin B12 is not commonly used in the body and is not typically found in dietary supplements or pharmaceuticals. Its overall biological significance is limited compared to Methylcobalamin.

Use in the Body:

Methylcobalamin - Has a very high absorption rate which allows it to be utilized by the body. It is the preferred form in supplements for individuals who suffer from B12 deficiencies and certain types of neuropathy. It is widely used in the medical setting for its efficacy in supporting nerve health and improving cognitive function.

Cyclocobalamin - Due to its synthetic nature and limited use, it is not typically found in supplements that are used for treating B12 deficiencies. This form is not commonly used in the medical setting which makes it less relevant for treatment of certain conditions.

Hydrate IV Therapy has always used methylcobalamin in our intravenous therapies and intramuscular shots. Its biologically active make-up makes it our preferred choice for our clients who utilize our services to combat the ailments of lowered levels of vitamin B12 in their body. It can enhance energy levels, support neurological health, improve mood, and aid in recovery from various conditions. Stop by Hydrate IV Therapy in Edina, MN for more information about this amazing vitamin and see the benefits for yourself!